Cells and Biologics

At Regenerative Medicine Dublin, we are pleased to provide all Cellular and Biologic treatments approved for use in Orthopaedics and Sports Medicine. We shall discuss these where we see them as an option for patients that have exhausted other conservative treatments (activity modification, physiotherapy, pain medication) but aren’t yet ready for surgery to improve their pain or function.

Overview

Our own blood, fat and bone marrow contain potent elements that naturally reduce inflammation and promote healing. By utilising these substances, including fat cells, platelet rich plasma and bone marrow derived cells in qualifying patients, our doctors are able to tap into the body’s own natural resources to either avoid or delay surgery, or improve the outcomes of operative intervention. In addition to cellular sources from within the body, we can also use lubricating medications and gels (Hyaluronic Acid) to improve movement and reduce inflammation in joints that are showing signs of wear and/ or pain.

Our Treatments

Fat Cells

Adipose tissue contains a high concentration of important reparative cells that may help support the healing process. Fat is minimally invasive to harvest and provides cushion and support to help the healing process. Research has shown that as a person ages, their FAT maintains its reparative properties unlike other similar tissue, which may lose healing capacity with age. 

Platelet Rich Plasma (PRP)

Platelet Rich Plasma is a concentration of platelets and growth factors created from a small amount of your own blood or bone marrow. Platelet rich plasma can enhance the body’s natural ability to heal and reduce inflammation in arthritic joints and tendons. Please include a “Learn More” or equivalent to link people back to PRP page.

Bone Marrow Cells (BMAC)

Bone marrow is an abundant resource of stem cells. Extracted from the inner cavity of the pelvis, humerus or tibia, these stem cells provide proteins that can promote healing and decrease inflammation. The product is referred to as bone marrow aspirate concentration (BMAC). Once extracted, the bone marrow is spun in a special device called a centrifuge so that the stem cells separate from other components. The isolated cells are then injected into the area of concern. The procedure can be performed in tandem with a surgical procedure or alone in an outpatient setting. There is increasing evidence that using bone-marrow-derived stem cells along with existing surgical techniques may improve outcomes, particularly for patients undergoing revision procedures.

Hyaluronic Acid / Viscosupplementation

Hyaluronic acid (HA) is a naturally occurring large molecule that helps to calm down inflammation. It also increases the expression of anti-inflammatory molecules in the knee and in cartilage cells, or ‘chondrocytes’. HA stimulates the cells that generate the synovial fluid in the knee, called synoviocytes. This, in turn, promotes the release of HA into the synovium and the synovial fluid. Together, these effects support the regulation (homeostasis), of the joints by calming down inflammation and helping to promote anti-inflammatory factors or proteins in the joints. HA helps to regulate the equilibrium of those factors if they are unbalanced, which can occur in patients with acute articular cartilage damage, and especially in both early and late osteoarthritis.

Nutraceuticals

Broadly speaking, ‘nutraceuticals’ are nutrients, supplements or other dietary products that are considered to have potential medicinal or physiological effects but do not fall within standard drug classifications. The term is loosely derived from ‘nutrition’ and ‘pharmaceutical’, and does not have a clear definition in the medical literature. However, it represents a series of approaches that have either established or potential benefits in the treatment of a wide range of conditions.

For arthritis and other conditions of the joints, cartilage or related areas, there are several nutraceuticals that can help alleviate pain and discomfort. These have the potential to replace, or at least help reduce, the use of more aggressive drug therapies. They are known for their extremely safe action, and in most cases are relatively inexpensive.

In some cases, there is now some data in the literature that suggests that several different nutraceutical approaches are beneficial in the treatment of cartilage and joint disorders. However, there remains some conflicting opinions on the efficacy of certain products, and this makes it imperative to discuss any products you are considering with your physician who will be able to offer you advice based on the current evidence available.

 

Stem Cell Research & Clinical Trials

Research activity in the field of Regenerative Medicine, Orthopaedics and Sports Medicine is among the most promising in all areas of modern healthcare. At Regenerative Medicine Dublin, our team are committed to providing patients with access to a promising collection of biological treatments.

Our orthopaedic doctors and research staff are involved developing and vetting these emerging therapies through basic science research and on-going clinical trials. The result has been the careful application of techniques that expand our offering of less invasive treatment options or augment our surgical solutions. In fact, with the proliferation of clinics offering regenerative medicine and alternative treatments for orthopedic conditions, our medical team warn patients to be wary of providers who aren’t using biologic treatments that have not been scientifically proven or researched. If you do wish to be considered for emerging clinical trials we shall be happy to discuss this with you.

Please find below a link to the AAOS Position Statement on the Use of Emerging Biologic Therapies